Biomaterials Related Infection Group

Biomaterials Related Infection research group

Aim

The aim of the research group is to investigate the causes and mechanisms of surgical infection, particularly that involving implantable devices, so as to advance treatment of such infections and particularly their prevention. Our research underpins our teaching, to undergraduates and postgraduates as well as training of senior doctors in international masterclasses. 

--Roger Bayston, Professor of Surgical Infection, Head of Biomaterials Related Infection Group

BRIG research

 

Research issues

Modern surgery often involves the use of devices made from biomaterials. These are prone to a particular type of infection, in which the research group has a special interest. Such surgery includes neurosurgery, critical care, trauma, spinal and orthopaedic surgery, ear infections, dialysis for kidney failure, and longterm bladder drainage.

Our research involves the causes of surgical infection, how to diagnose and treat it more efficiently, and importantly how to prevent it. Much of our research is on development of antimicrobial materials for surgical use and we already have some of these in clinical use.

What we are doing about...

1. Causes of surgical infection

 

2. Orthopaedic infections

 

3. Neurosurgical infections

 

4. Ear infections

 

5. Peritoneal dialysis

 

6. Longterm urinary catheters

 

Current projects

  • Prevention of external fixator pin site infection with a novel antibiotic-impregnated collar (J Walker, R Bayston, B Scammell, Arthritis Research UK Fellowship 2010)
  • Efficacy of pre-operative patient skin preparation using Chloraprep (R Bayston, B Scammell, Waheed Ashraf, Lisa Whittington)
  • Suitablility of current antibiotic prophylaxis for neck of femur fractures and arthroplasty (R Bayston, B scammell, W Ashraf, Jenny Paterson)
  • All projects

 

Outcomes

Patent

Professor Bayston has established the clinical and commercial viability of the platform technology and his strong interest in antimicrobial biomaterials has resulted in a patented process which has been used to develop a clinically successful "anti-infective" hydrocephalus shunt, with over 150,000 recipients worldwide, and a device for neurocritical care with over 750,000 patients worldwide.

read more

 

Publications in leading peer-reviewed journals

Our research has been published in leading journals. Please see publications records under the individual profiles of our members.   

 

 

 

 

Biomaterials Related Infection Group

Division or Rheumatology, Orthopaedics and Dermatology
The University of Nottingham
C Floor, West Block, Queen's Medical Centre
Nottingham, NG7 2UH


telephone: +44 (0) 115 823 1115
email:oas-admin@nottingham.ac.uk