Centre of Evidence Based Dermatology
Cellulitisindex

Cellulitis research    

Cellulitis is a very common but relatively under-researched skin condition
 
Research overview
 

Cellulitis is a serious and painful infection of the skin and underlying tissue. It commonly occurs on legs and arms, and can spread rapidly if left untreated.

Although cellulitis is very common, there are still many gaps in our understanding of how best to diagnose, treat and prevent it.    

This webpage describes our work in defining the research agenda for future research into cellulitis, and describes our practice-changing research (see the PATCH I and PATCH II trials) which has influenced recommendations made in clinical guidelines from around the world.  

Ongoing projects
 

 The COAT Study - A study assessing the effectiveness and safety of a 5-day treatment versus the standard 7-day treatment of flucloxacillin for cellulitis. 

 
 

Outcomes & diagnostics

None at present.
 

Resources

Map of systematic reviews on cellulitis - Comprehensive categorized list of systematic reviews published on cellulitis. Updated monthly.
 
 

All projects

ProjectDescriptionFundingStatus
The COAT Study A study assessing the effectiveness and safety of a 5-day treatment versus the standard 7-day treatment of flucloxacillin for cellulitis.  NIHR HTA 134867 Ongoing
Cellulitis Priority Setting Partnership (PSP) Establishing uncertainties in relation to the treatment and prevention of cellulitis that should be prioritised for further research UK Dermatology Trials Network Published
Prophylactic Antibiotics for the Treatment of Cellulitis at Home (PATCH) I trial Randomised controlled trial to investigate whether prophylactic antibiotics (taken for 12 months) can prevent further episodes of cellulitis of the leg Action Medical Research Published
Prophylactic Antibiotics for the Treatment of Cellulitis at Home (PATCH) II trial Randomised controlled trial to investigate whether prophylactic antibiotics (taken for 6 months) can prevent further episodes of cellulitis of the leg BUPA Foundation Published

Centre of Evidence Based Dermatology

The University of Nottingham
Applied Health Research Building
University Park, Nottingham
NG7 2RD


telephone: +44 (0) 115 84 68631
email: cebd@nottingham.ac.uk