Tumours of the skin, soft tissue and bone
One of the key aims of the cancer research team here at Nottingham is to explore cancer without species boundaries, enabling us to address areas of unmet clinical need.
Tumours of the skin, soft tissue and bone are often aggressive cancers, which can be difficult to treat. There is an urgent need to develop both effective treatments and better prognostic markers to predict how these tumours behave.
Our researchers are investigating these tumours when they occur spontaneously in companion animal species. Together, they aim to deliver bench-to-bedside improvements within both the veterinary and medical fields.
Spotlight project
What can different dog breeds tell us about cancer?
The incidence of some tumour types, such as osteosarcoma and mast cell tumours, appears to be increased in certain breeds of dog. While several factors are known to influence the development of these cancers, a number of genes are thought to be involved in the increased risk among certain breeds.
Our research team is investigating how these genes may predispose some breeds to particular tumour types, as well as determining the molecular mechanisms driving the progression of these tumours. Their work is helping to develop improved diagnostic and therapeutic approaches.
Read our studies on canine tumours