To find out how NBIC can assist you with the use of these facilities, please contact NBIC admin: LS-NBIC@exmail.nottingham.ac.uk
Managed Chemical Compound Collection
The University of Nottingham has an established state-of-the-art fully automated and integrated Managed Chemical Compound Collection Facility.
The facility provides a screening resource for the identification of chemical starting points as drug leads against drug targets of interest.
The diversity of the compounds in the compound library (as evidenced by the low pairwise Tanimoto score), combined with their lead-like characteristics, makes the library an ideal source for primary screening of your drug target.
The facility offers screening ready samples of compounds that can be tested directly in your assay. Typically, this would allow screening at a concentration of 100 uM in your primary assay.
Compounds can be dispensed in consultation with the end user to allow screening under desired assay conditions.
Samples can be supplied based upon your own selection of compounds from the collection:
- this can be a random selection from the collection
- the full collection
- a subset of virtual screening hits from the collection
For further information please contact Dr Lodewijk Dekker at lodewijk.dekker@nottingham.ac.uk
ISAC
ISAC is a University of Nottingham (UoN) centre of excellence in surface and interface analytics in partnership with the UK's national metrology institute the National Physical Laboratory (NPL).
ISAC
Flow Cytometry Facility
Provides access to high end flow cytometers as well as a full range of training and support designed to make your flow cytometry experiments a success.
Flow cytometry facility
Nottingham Biomedical Research Centre
Nottingham’s expertise in translational imaging will enable step-changes in medical treatment and understanding of disease mechanisms
The cross cutting MRI theme is a strategic initiative designed to support and drive innovative imaging approaches in all of our research themes.
The MRI theme builds on internationally recognised expertise in the development of novel MRI approaches and state of the art facilities.
Nottingham Biomedical Research Centre
Nanoscale and Microscale Research Centre
The Nanoscale and Microscale Research Centre (nmRC) is a cross-disciplinary facility dedicated to supporting and promoting world-leading nanoscience and materials characterisation.
With state-of-the-art facilities allied to in-house technical and academic expertise, the centre offers a diverse range of research and commercial capabilities. The centre is proud host to a unique suite of 20 instruments which facilitate the imaging and analytical investigation of materials from a wide range of scientific disciplines.
The NMRC includes the 3DOrbiSIMS production instrument which to date is the only one in the world. This instrument has the capability to perform label-free chemical imaging of biofilms, materials, cells and tissues. The 3DOrbiSIMS provides next-generation resolution in ToF-SIMS, which will help unlock the potential in understanding why microbes colonise certain materials and not others, in addition to dissecting the intricate interactions in polymicrobial communities.
Nanoscale and Microscale Research Centre
Pre-clinical Imaging Research Laboratories
The Medical Imaging Unit (MIU) in the School of Medicine is available for clinicians and scientists who wish to use MRI techniques to enhance their research using the state-of-the-art University facilities.
Launched in 2012, the Unit comprises MRI, PET CT and Gamma camera facilities and is housed within the University of Nottingham Medical School. We also provide access to a dedicated team of staff to facilitate a varied portfolio of imaging-based research.
Medical Imaging Unit
School of Life Sciences Imaging
School of Life Sciences Imaging (SLIM) provides access to cutting-edge imaging technology and expertise to researchers across the University and the business community.
The imaging facilities span across three research areas, these are: School of Life Sciences Imaging Platform, Centre of Membrane Proteins and Receptors (COMPARE) and the Biodiscovery Institute (BDI).
The resources in SLIM are supported by an experienced 5-person team with a combined 100+ years expertise in microscopy, image-analysis, and sample-preparation. Both collaborative projects and service work are available to external users.