Schematic showing sample preparation method for analysis of polymer microparticles
Dr Adam Dundas, Dr Stefanie Kern, Professor Morgan Alexander, and other members of the Biomaterials Discovery team have published their latest research on the development of a particle sample preparation method for surface analysis. By mounting particles onto a poly(hydroxyethyl) methacrylate solution, particles are entrapped by the polymer, securing the particles for surface analysis techniques such as ToF-SIMS. By using a simple polymer solution, this vastly reduces the PDMS contamination compared to alternative mounting techniques such as adhesive tapes. By ensuring PDMS is removed from the sample preparation method, any PDMS contamination introduced by the manufacturing process can easily be identified and therefore improving the quality assessment of manufactured particles.
The full article can be read in the Surface and Interface Analysis journal.
A new particle mounting method for surface analysis Adam A. Dundas, Stefanie Kern, Valentina Cuzzucoli Crucitti, David J. Scurr, Ricky Wildman, Derek J. Irvine, Morgan R. Alexander Surf Interface Anal. 2021; 1-7 https://doi.org/10.1002/sia.7010
Advanced Materials and Healthcare Technologies, School of Pharmacy, The University of Nottingham University Park Nottingham, NG7 2RD
telephone: +44 (0) 115 846 6246 email: BiomaterialsDiscovery@nottingham.ac.uk