NEGM, O. H., AHMAD, O., FIGUEREDO, G. P., HAMED, M. R., POLLARD, L., GARIBALDI, J., SEWELL, H. and ROBERTSON, J. F., 2018. VALIDATION OF AN AUTOANTIBODY BLOOD TEST FOR THE DETECTION OF EARLY BREAST CANCER (BC), PARTICULARLY HORMONE RECEPTOR POSITIVE BC BRITISH JOURNAL OF SURGERY. 105, 34-35
NEGM, OLA H., AHMED, OMAR, FIGUEREDO, GRAZZIELA PATROCINIO, HAMED, MOHAMED R., POLLARD, LUCAS, GARIBALDI, JONATHAN, SEWELL, HERB and ROBERTSON, JOHN F., 2018. Validation of an autoantibody blood test for the detection of early breast cancer (BC), particularly hormone receptor positive BC CANCER RESEARCH. 78(4),
SHORTALL, SINEAD E, NEGM, OLA H, FOWLER, MAXINE, FAIRCLOUGH, LUCY C, TIGHE, PATRICK J, WIGMORE, PETER M and KING, MADELEINE V, 2018. 6 Receptor Antagonist SB-399885. Molecular neurobiology.
TUBBY C, NEGM OH, HARRISON T, TIGHE PJ, TODD I and FAIRCLOUGH LC, 2017. Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction. The Journal of asthma : official journal of the Association for the Care of Asthma. 54(5), 456-466 SHINDI, REHAM, ALMEHAIRI, AMNA, NEGM, OLA H., KALSHEKER, NOOR, GALE, NICHOLA S., SHALE, DENNIS J., HARRISON, TIMOTHY W., BOLTON, CHARLOTTE E., JOHN, MICHELLE, TODD, IAN, TIGHE, PATRICK J. and FAIRCLOUGH, LUCY C., 2017. Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease CLINICAL IMMUNOLOGY. 183, 344-353 TODD, IAN, NEGM, OLA H., REPS, JENNA, RADFORD, PAUL, FIGUEREDO, GRAZZIELA, MCDERMOTT, ELIZABETH M., DREWE, ELIZABETH, POWELL, RICHARD J., BAINBRIDGE, SUSAN, HAMED, MOHAMED, CROUCH, SHARON, GARIBALDI, JON, ST-GALLAY, STEVE, FAIRCLOUGH, LUCY C. and TIGHE, PATRICK J., 2017. A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing PHARMACOLOGICAL RESEARCH. 125, 188-200 MONAGHAN, TANYA M., NEGM, OLA H., MACKENZIE, BRENDON, HAMED, MOHAMED R., SHONE, CLIFFORD C., HUMPHREYS, DAVID P., ACHARYA, K. RAVI and WILCOX, MARK H., 2017. High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY. 10, 169-175 NEGM, O. H., MACKENZIE, B., HAMED, M. R., AHMAD, O. A. J., SHONE, C. C., HUMPHREYS, D. P., ACHARYA, K. RAVI, LOSCHER, C. E., MARSZALOWSKA, I., LYNCH, M., WILCOX, M. H. and MONAGHAN, T. M., 2017. Protective antibodies against Clostridium difficile are present in intravenous immunoglobulin and are retained in humans following its administration CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 188(3), 437-443 AYLING, K., BOWDEN, T., TIGHE, P., TODD, I., DILNOT, E. M., NEGM, O. H., FAIRCLOUGH, L. and VEDHARA, K., 2017. The application of protein microarray assays in psychoneuroimmunology BRAIN BEHAVIOR AND IMMUNITY. 59, 62-66 NEGM, O. H., MUFTAH, A. A., ALESKANDARANY, M. A., HAMED, M. R., AHMAD, D. A., NOLAN, C. C., DIEZ-RODRIGUEZ, M., TIGHE, P. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. Clinical utility of reverse phase protein array for molecular classification of breast cancer: Breast Cancer Res Treat Breast cancer research and treatment. 155(1), 25-35 ALESKANDARANY, M. A., AGARWAL, D., NEGM, O. H., BALL, G., ELMOUNA, A., ASHANKYTY, I., NUGLOZEH, E., FAZALUDEEN, M. F., DIEZ-RODRIGUEZ, M., NOLAN, C. C., TIGHE, P. J., GREEN, A. R., ELLIS, I. O. and RAKHA, E. A., 2016. The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts: Breast Cancer Res Treat Breast cancer research and treatment. ALESKANDARANY, MOHAMMED A., AGARWAL, DEVIKA, NEGM, OLA H., BALL, GRAHAM, ELMOUNA, AHMED, ASHANKYTY, IBRAHEEM, NUGLOZEH, EDEM, FAZALUDEEN, MOHAMMAD F., DIEZ-RODRIGUEZ, MARIA, NOLAN, CHRISTOPHER C., TIGHE, PATRICK J., GREEN, ANDREW R., ELLIS, IAN O. and RAKHA, EMAD A., 2016. The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts BREAST CANCER RESEARCH AND TREATMENT. 156(1), 9-20 SALAZAR, F., HALL, L., NEGM, O. H., AWUAH, D., TIGHE, P. J., SHAKIB, F. and GHAEMMAGHAMI, A. M., 2016. The mannose receptor negatively modulates the Toll-like receptor 4-aryl hydrocarbon receptor-indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization: J Allergy Clin Immunol J Allergy Clin Immunol. 137(6), 1841-1851 e2 NEGM, OLA H., MUFTAH, ABIR A., ALESKANDARANY, MOHAMMED A., HAMED, MOHAMED R., AHMAD, DENA A. J., NOLAN, CHRISTOPHER C., DIEZ-RODRIGUEZ, MARIA, TIGHE, PATRICK J., ELLIS, IAN O., RAKHA, EMAD A. and GREEN, ANDREW R., 2016. Clinical utility of reverse phase protein array for molecular classification of breast cancer BREAST CANCER RESEARCH AND TREATMENT. 155(1), 25-35 AHMAD DA, NEGM OH, ALABDULLAH ML, MIRZA S, HAMED MR, BAND V, GREEN AR, ELLIS IO and RAKHA EA, 2016. Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers. Breast cancer research and treatment. 159(3), 457-67 NEGM, O. H., MUFTAH, A. A., ALESKANDARANY, M. A., HAMED, M. R., AHMAD, D. A. J., NOLAN, C. C., RODRIGUEZ, M. D., TIGHE, P. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. The Merits of Reverse Phase Protein Array for Molecular Classification of Breast Cancer JOURNAL OF PATHOLOGY. 240, 15-15
NEGM, O. H., KARIM, H. H., MANGER, K., HASSALL, J., FADHIL, W., TIGHE, P. J. and ILYAS, M., 2016. Comparative Analysis of Primary Tumour and Matched Metastasis in Colorectal Cancer Patients; Investigate Genomic, Transcription and Translational Profiles JOURNAL OF PATHOLOGY. 240, 17-17
NEGM, O. H., HASSALL, J. C., FADHILL, W., PITIOT, A., MARCHESSOUX, C., TIGHE, P. J. and ILYAS, M., 2016. BerEP4 and AE1/3 are Reliable Markers of Epithelial Content for Biomarker Discovery Using Reverse Phase Protein Arrays (RPPA) JOURNAL OF PATHOLOGY. 240, 37-37
MOZ, STEFANIA, BASSO, DANIELA, BOZZATO, DANIA, GALOZZI, PAOLA, NAVAGLIA, FILIPPO, NEGM, OLA H., ARRIGONI, GIORGIO, ZAMBON, CARLO-FEDERICO, PADOAN, ANDREA, TIGHE, PADDY, TODD, IAN, FRANCHIN, CINZIA, PEDRAZZOLI, SERGIO, PUNZI, LEONARDO and PLEBANI, MARIO, 2016. SMAD4 loss enables EGF, TGF beta 1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells ONCOTARGET. 7(43), 69927-69944 AHMAD, DENA A. J., NEGM, OLA H., ALABDULLAH, M. LAYTH, MIRZA, SAMEER, HAMED, MOHAMED R., BAND, VIMLA, GREEN, ANDREW R., ELLIS, IAN O. and RAKHA, EMAD A., 2016. Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers BREAST CANCER RESEARCH AND TREATMENT. 159(3), 457-467 ALSHAREEDA, ALAA TARIG, NEGM, OLA H., ALESKANDARANY, MOHAMMED A., GREEN, ANDREW R., NOLAN, CHRISTOPHER, TIGHHE, PATRICK J., MADHUSUDAN, SRINIVASAN, ELLIS, IAN O. and RAKHA, EMAD A., 2016. Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein BREAST CANCER RESEARCH AND TREATMENT. 159(1), 41-53 NEGM, OLA H., HAMED, MOHAMED R., SCHOEN, ROBERT E., WHELAN, RICHARD L., STEELE, ROBERT J., SCHOLEFIELD, JOHN, DILNOT, ELIZABETH M., KUMARA, H. M. C. SHANTHA, ROBERTSON, JOHN F. R. and SEWELL, HERBERT F., 2016. Human Blood Autoantibodies in the Detection of Colorectal Cancer PLOS ONE. 11(7), ABDULJABBAR R, AL-KAABI MM, NEGM OH, JERJEES D, MUFTAH AA, MUKHERJEE A, LAI CF, BULUWELA L, ALI S, TIGHE PJ, GREEN A, ELLIS I and RAKHA E, 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer. Breast cancer research and treatment. 150(3), 511-22 ABDULJABBAR R, NEGM OH, LAI C, JERJEES DA, AL-KAABI M, HAMED MR, TIGHE PJ, BULUWELA L, MUKHERJEE A, GREEN AR, ALI S, RAKHA EA and ELLIS IO, 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Breast cancer research and treatment. 150(2), 335-46 JERJEES DA, NEGM OH, ALABDULLAH ML, MIRZA S, ALKAABI M, HAMEED MR, ABDULJABBAR R, MUFTAH A, NOLAN CC, GREEN AR, TIGHE PJ, BAND V, ELLIS IO and RAKHA EA, 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways. Breast cancer research and treatment. 150(1), 91-103 ABDULJABBAR, REZVAN, NEGM, OLA H., LAI, CHUN-FUI, JERJEES, DENA A., AL-KAABI, METHAQ, HAMED, MOHAMED R., TIGHE, PATRICK J., BULUWELA, LAKJAYA, MUKHERJEE, ABHIK, GREEN, ANDREW R., ALI, SIMAK, RAKHA, EMAD A. and ELLIS, IAN O., 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer BREAST CANCER RESEARCH AND TREATMENT. 150(2), 335-346 FAIRCLOUGH, LUCY C., STOOP, A. ALLART, NEGM, OLA H., RADFORD, PAUL M., TIGHE, PATRICK J. and TODD, IAN, 2015. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome EUROPEAN JOURNAL OF IMMUNOLOGY. 45(10), 2937-2944 ABDULJABBAR, REZVAN, AL-KAABI, METHAQ MUEEN, NEGM, OLA H., JERJEES, DENA, MUFTAH, ABIR A., MUKHERJEE, ABHIK, LAI, CHUN F., BULUWELA, LAKI, ALI, SIMAK, TIGHE, PATRICK J., GREEN, ANDREW, ELLIS, IAN and RAKHA, EMAD, 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer BREAST CANCER RESEARCH AND TREATMENT. 150(3), 511-522 GRECO, ELIANA, AITA, ADA, GALOZZI, PAOLA, GAVA, ALESSANDRA, SFRISO, PAOLO, NEGM, OLA H., TIGHE, PATRICK, CASO, FRANCESCO, NAVAGLIA, FILIPPO, DAZZO, EMANUELA, DE BORTOLI, MARZIA, RAMPAZZO, ALESSANDRA, OBICI, LAURA, DONADEI, SIMONA, MERLINI, GIAMPAOLO, PLEBANI, MARIO, TODD, IAN, BASSO, DANIELA and PUNZI, LEONARDO, 2015. The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-kappa B pathway ARTHRITIS RESEARCH & THERAPY. 17, JERJEES, D. A., NEGM, O. H., ALABDULLAH, M. L., ALKAABI, M., MIRZA, S., ABDULAJABBAR, R., MUFTAH, A., GREEN, A. R., TIGHE, P. J., BAND, V., ELLIS, I. O. and RAKHA, E. A., 2015. Reverse Phase Protein Array is a Useful High Throughput Technique for Assessment of Multiple Proteins in Breast Cancer JOURNAL OF PATHOLOGY. 237, S30-S30
NEGM, OLA H., HAMED, MOHAMED R., DILNOT, ELIZABETH M., SHONE, CLIFFORD C., MARSZALOWSKA, IZABELA, LYNCH, MARK, LOSCHER, CHRISTINE E., EDWARDS, LAURA J., TIGHE, PATRICK J., WILCOX, MARK H. and MONAGHAN, TANYA M., 2015. Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis CLINICAL AND VACCINE IMMUNOLOGY. 22(9), 1033-1039 ALSHAREEDA, A. T., NEGM, O. H., GREEN, A. R., NOLAN, C. C., TIGHE, P., ALBARAKATI, N., SULTANA, R., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer BRITISH JOURNAL OF CANCER. 112(12), 1929-1937 JERJEES, DENA A., NEGM, OLA H., ALABDULLAH, M. LAYTH, MIRZA, SAMEER, ALKAABI, METHAQ, HAMEED, MOHAMED R., ABDULJABBAR, REZVAN, MUFTAH, ABIR, NOLAN, CHRIS C., GREEN, ANDREW R., TIGHE, PATRICK J., BAND, VIMLA, ELLIS, IAN O. and RAKHA, EMAD A., 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways BREAST CANCER RESEARCH AND TREATMENT. 150(1), 91-103 GALOZZI, P, NEGM, O, GRECO, E, ALKHATTABI, N, GAVA, A, SFRISO, P, FAIRCLOUGH, L, TODD, I, TIGHE, P and PUNZI, L, 2015. Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome. Reumatismo. 66(4), 277-84
ALESKANDARANY, M. A., NEGM, O. H., TIGHE, P., NOLAN, C., GREEN, A. R., RAKHA, E. A. and ELLIS, I. O., 2015. The Prognostic Significance of STAT3 Expression in Invasive Breast Cancer: an Immunohistochemical and Reverse Phase Protein Array Study JOURNAL OF PATHOLOGY. 237, S32-S32
JERJEES, D. A., NEGM, O. H., ALABDULLAH, M. L., ALESKANDARANY, M., MIRZA, S., GREEN, A. R., TIGHE, P. J., BAND, V., ELLIS, I. O. and RAKHA, E. A., 2015. Mitogen Activated Protein Kinase Signalling Proteins are Associated with Good Prognosis in Breast Cancer and are Mainly Related to Estrogen Receptor JOURNAL OF PATHOLOGY. 237, S18-S18
MUFTAH, A. A., NEGM, O. H., ALESKANDARANY, M., AL-KAABI, M. M., JERJEES, D. A., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2015. Successful Alignment of Macrodissected FFPE Tissue to Nottingham Prognostic Index Plus (NPI plus ) Classes Using RPPA Technology JOURNAL OF PATHOLOGY. 237, S30-S30
NEGM, OLA H., MANNSPERGER, HEIKO A., MCDERMOTT, ELIZABETH M., DREWE, ELIZABETH, POWELL, RICHARD J., TODD, IAN, FAIRCLOUGH, LUCY C. and TIGHE, PATRICK J., 2014. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS) EUROPEAN JOURNAL OF IMMUNOLOGY. 44(7), 2096-2110 SELVARAJAH, SENTHOORAN, NEGM, OLA H, HAMED, MOHAMED R, TUBBY, CAROLYN, TODD, IAN, TIGHE, PATRICK J, HARRISON, TIM and FAIRCLOUGH, LUCY C, 2014. Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators of inflammation. 2014, 820304
ALESKANDARANY, MOHAMMED A., NEGM, OLA H., GREEN, ANDREW R., AHMED, MOHAMED A. H., NOLAN, CHRISTOPHER C., TIGHE, PATRICK J., ELLIS, IAN O. and RAKHA, EMAD A., 2014. Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study BREAST CANCER RESEARCH AND TREATMENT. 145(2), 339-348 SELVARAJAH, SENTHOORAN, NEGM, OLA H., HAMED, MOHAMED R., TUBBY, CAROLYN, TODD, IAN, TIGHE, PATRICK J., HARRISON, TIM and FAIRCLOUGH, LUCY C., 2014. Development and Validation of Protein Microarray Technology for Simultaneous Inflammatory Mediator Detection in Human Sera MEDIATORS OF INFLAMMATION. ALSHAREEDA, ALAA T., NEGM, OLA H., GREEN, ANDREW R., NOLAN, CHRISTOPHER, TIGHE, PADDY, ALBARAKATI, NADA, SULTANA, REBEKA, MADHUSUDAN, SRINIVASAN, ELLIS, IAN O. and RAKHA, EMAD A., 2014. SUMOylation proteins in breast cancer BREAST CANCER RESEARCH AND TREATMENT. 144(3), 519-530 TIGHE, P., NEGM, O., TODD, I. and FAIRCLOUGH, L., 2013. Utility, reliability and reproducibility of immunoassay multiplex kits Methods. 61(1), 23-29 ALSHAREEDA AT, NEGM OH, ALBARAKATI N, GREEN AR, NOLAN C, SULTANA R, MADHUSUDAN S, BENHASOUNA A, TIGHE P, ELLIS IO and RAKHA EA, 2013. Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer. Breast cancer research and treatment. 139(2), 301-10 ALSHAREEDA, ALAA T., NEGM, OLA H., ALBARAKATI, NADA, GREEN, ANDREW R., NOLAN, CHRISTOPHER, SULTANA, REBEKA, MADHUSUDAN, SRINIVASAN, BENHASOUNA, AHMED, TIGHE, PADDY, ELLIS, IAN O. and RAKHA, EMAD A., 2013. Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer BREAST CANCER RESEARCH AND TREATMENT. 139(2), 301-310 ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., AHMED, M. A. H., NOLAN, C. C., TIGHE, P. J., GREEN, A. R. and ELLIS, I. O., 2013. Epithelial Mesenchymal Transition in Early Invasive Breast Cancer: Further Evidence Using Reverse Phase Protein Array JOURNAL OF PATHOLOGY. 231, 19-19
NEGM, O. H., MCDERMOTT, E. M., DREWE, E., POWELL, R., FAIRCLOUGH, L., TODD, I. and TIGHE, P., 2013. Comprehensive intracellular inflammatory pathways study in TRAPS patients IMMUNOLOGY. 140, 182-182
ABD EL-WAHED, M. M., SAKR, S. A., EL-SAHRA, D. G., NEGM, O. H. and ALESKANDARANY, M. A., 2013. Prostatic Adenocarcinoma versus Urothelial Carcinoma among Egyptian Patients: an Immunohistochemical Study JOURNAL OF PATHOLOGY. 231, 43-43
NEGM, O. H., ALSHAREEDA, A. T., ALESKANDARANY, M. A., GREEN, A. G., ELLIS, I. O., RAKHA, E. A. and TIGHE, P. J., 2013. Breast Cancer Proteomic Profiling Using Reverse Phase Protein Array (RPPA) JOURNAL OF PATHOLOGY. 231, 13-13
ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., AHMED, M. A., NOLAN, C. C., BALL, G. R., CALDAS, C., GREEN, A. R., TIGHE, P. J. and ELLIS, I. O., 2012. TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome Breast cancer research and treatment. 136(2), 419-27 ALESKANDARANY, MOHAMMED A., NEGM, OLA H., RAKHA, EMAD A., AHMED, MOHAMED A. H., NOLAN, CHRISTOPHER C., BALL, GRAHAM R., CALDAS, CARLOS, GREEN, ANDREW R., TIGHE, PATRICK J. and ELLIS, IAN O., 2012. TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome BREAST CANCER RESEARCH AND TREATMENT. 136(2), 419-427 ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., HASAN, M. A., GREEN, A. R., TIGHE, P. and ELLIS, I. O., 2012. Cadherin Switch in Early Invasive Breast Cancer: a Reverse Phase Protein Microarray Study JOURNAL OF PATHOLOGY. 228, S13-S13