Prof Needham has submitted a patent application on a new anti-COVID nasal spray

Professor David Needham has submitted a patent application on a new anti-COVID nasal spray and a paper published in Pharmaceutical Research.

The patent - Niclosamide nasal and throat spray: 
The present disclosure provides prophylactic pH-buffered solution of niclosamide that can be used as a nasal and throat spray to prevent initial infection of COVID19, its more contagious variants, and other respiratory viral infections. It also provides a method of making such solution that does not require excess niclosamide to be dissolved in aqueous media. Furthermore, it describes a method for extracting niclosamide from commercially available tablets into aqueous solution that does not involve the use of organic solvents. 

David Needham, The pH dependence of niclosamide solubility, dissolution, and morphology: Motivation for potentially universal mucin-penetrating nasal and throat sprays for COVID19, its variants and other viral infections, Pharmaceutical Research, 2021. DOI: 10.1007/s11095-021-03112-x