Kerr Lab, Nottingham,

ABC Transporter Research

 

  Research |   Publications |    Group  |   Protocols   |   Opportunities  |  Collaborators | Homepage

Who do we work with?

Dr. Richard Callaghan, ANU Canberra

I did my Wellcome Trust Career Development Fellowship in Oxford working alongside Rich and his group. Now that Richard has returned to Australia we continue to collaborate on both functional and structural aspects of P-gp, ABCG2, ABCA4 and PfCRT.

Dr. Beth Coyle, University of Nottingham

With Beth's lab we are investigating the role of the multidrug ABC transporters in the resistance to chemotherapy in children's brain tumours. We have jointly supervised several PhD students and the published fruits of this collaboration are starting to appear. For example see this paper and associated press release

Professor Gill Stephens, University of Nottingham

With Gill's lab we are starting to look at how transporters could be used in bioengineering. We have two PhD students and external funding from industry to explore this question.

Dr Frederica Theodoulou, Rothamsted Research

Freddie is plant ABC person, and we've worked on and off over the past few years on the long chain fatty acid transporters of the peroxisome.

Professor Malcolm Bennett, University of Nottingham

Work between the two groups aims to understand the molecular events leading to auxin transport in plant root cells. We have published papers in Plant Cell, Nature Cell Biology and Plant Physiology describing the current research into the Arabidopsis putative auxin permease, Aux1, and continue to investigate this in plants and in vitro.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Highlight Box

March 2021. New bioinformatics paper on a structural motif responsible for ABCG family functional divergence.

 

February 2021. New paper with Beth Coyle’s group on the role of TWIST1 and ABCB1 in medulloblastoma migration.

 

January 2021. New paper with Tony Bishopp’s group on regulation of plant cytokinin signalling

 

January 2021. New article with Sue-Mien Then and colleagues at UoNM on interaction of ABCG2 with vitamin E derivatives

  

December 2020 new review with Ingrid Gelissen and Shereen Aleidi about the interaction of lipids with ABCG proteins.

 

November 2020 New review with Karl Kuchler, Erik Lee and Thomas Stockner on picky and promiscuous ABCG family proteins.

 

November 2020. New paper with Beth Coyle on hydrogel models of medulloblastoma

 

November 2020. New review with Beth Coyle on the unexplored role of YBX1 in childrens brain tumours

 

April 2020. New paper with Richard Callaghan on combining multiple techniques to interrogate ABCB1 structure and dynamics

 

February 2020. New paper on using FCS to measure ABCG2:drug interaction

 

January 2020. New paper on the constant contact interface in ABCG2.

 

August 2019 new paper with Beth Coyle on the role of ABCB1 in ependymoma.

 

 

 

 

This Web Page Created with PageBreeze Free HTML Editor