Physiological effects on major organs
Select the body organs to reveal further information about the physiological effects of sepsis.
The Brain
Causes confusion
Reduced circulating volume leads to confusion and reduced consciousness
The Liver
Raised liver function tests
Affecting glucose and coagulation control
Multiple Organ Failure
Cardiovascular insufficiency
Myocardial depression affecting heart rate and blood pressure
Hypotension
Tachycardia
Renal insufficiency
Acute Kidney Injury (AKI) occurs due to a drop in blood pressure which reduces the flow of blood to the kidneys.
The production of toxins during sepsis cause micro-emboli to block the renal tubules exacerbating the acute renal failure.