Helena Henke

Contact

• workRoom C03 Coates Building
  University Park
  Nottingham
  NG7 2RD
  UK
• Helena.Henke@nottingham.ac.uk

Biography

Helena studied chemistry at the University of Vienna (Austria) with a diploma thesis on metal complexes as anticancer agents in the group of Bernhard Keppler and graduated with a Mag. rer. nat. Her PhD studies took her to the Johannes Kepler University Linz (Austria) where they completed their PhD on the synthesis of polyphosphazenes with controlled dimensions and unique architectures and their application as nanomedicines under the guidance of Ian Teasdale. She carried out post doctoral research stays in Austria (Johannes Keppler University, Linz), Portugal (CQM - Centro de Química da Madeira), France (IMP - Laboratoire Ingénierie des Matériaux Polymères, Université Claude Bernard Lyon 1) before joining the group of Derek Irvine here at the University of Nottingham

Teaching Summary

Lecturer:

Introduction to Chemistry of Polymers - Lecture

Introduction to Chemistry of Polymers - Exercise

Introductory Lab Course

Exercise in Kinetics, Catalysis and Reaction Engineering

Polymer Chemistry Exercises, Unit 8 and 10

Co-supervisor:

13 Bachelor Theses and 4 Master Theses

Recent Publications

• QUINONES, JAVIER PEREZ, ROSCHGER, CORNELIA, ITURMENDI, AITZIBER, HENKE, HELENA, ZIERER, ANDREAS, PENICHE-COVAS, CARLOS and BRUEGGEMANN, OLIVER, 2022. Polyphosphazene-Based Nanocarriers for the Release of Camptothecin and Epirubicin PHARMACEUTICS. 14(1),
• STRASSER, PAUL, PLAVCAN, OLIVER, AJVAZI, EDIP, HENKE, HELENA, BRUGGEMANN, OLIVER and TEASDALE, IAN, 2022. Hetero and homo alpha,omega-chain-end functionalized polyphosphazenes JOURNAL OF POLYMER SCIENCE. 60(13), 2000-2007
• AITZIBER ITURMENDI, HELENA HENKE, GEORGE S. PAPPAS and IAN TEASDALE, 2021. Chapter 2 - Polyphosphazenes: macromolecular structures, properties, and their methods of synthesis. In: EWAN J.M. HAMILTON, ed., Synthetic Inorganic Chemistry Elsevier. 47-101
• IAN TEASDALE, OLIVER BRÜGGEMANN and HELENA HENKE, 2020. Polyphosphazenes for Medical Applications De Gruyter.

• View all publications

Past Research

Poly(organo)phosphazenes: Synthesis, characterization and medical application (drug delivery, tissue engineering)

Polymer therapeutics

Living polymerization techniques

Polymer synthesis

Ruthenium-arene complexes for tumor therapeutics

• QUINONES, JAVIER PEREZ, ROSCHGER, CORNELIA, ITURMENDI, AITZIBER, HENKE, HELENA, ZIERER, ANDREAS, PENICHE-COVAS, CARLOS and BRUEGGEMANN, OLIVER, 2022. Polyphosphazene-Based Nanocarriers for the Release of Camptothecin and Epirubicin PHARMACEUTICS. 14(1),
• STRASSER, PAUL, PLAVCAN, OLIVER, AJVAZI, EDIP, HENKE, HELENA, BRUGGEMANN, OLIVER and TEASDALE, IAN, 2022. Hetero and homo alpha,omega-chain-end functionalized polyphosphazenes JOURNAL OF POLYMER SCIENCE. 60(13), 2000-2007
• AITZIBER ITURMENDI, HELENA HENKE, GEORGE S. PAPPAS and IAN TEASDALE, 2021. Chapter 2 - Polyphosphazenes: macromolecular structures, properties, and their methods of synthesis. In: EWAN J.M. HAMILTON, ed., Synthetic Inorganic Chemistry Elsevier. 47-101
• IAN TEASDALE, OLIVER BRÜGGEMANN and HELENA HENKE, 2020. Polyphosphazenes for Medical Applications De Gruyter.
• QUINONES, JAVIER PEREZ, ITURMENDI, AITZIBER, HENKE, HELENA, ROSCHGER, CORNELIA, ZIERER, ANDREAS and BRUEGGEMANN, OLIVER, 2019. Polyphosphazene-based nanocarriers for the release of agrochemicals and potential anticancer drugs JOURNAL OF MATERIALS CHEMISTRY B. 7(48), 7783-7794
• LINHARDT, ANNE, KOENIG, MICHAEL, ITURMENDI, AITZIBER, HENKE, HELENA, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2018. Degradable, Dendritic Polyols on a Branched Polyphosphazene Backbone INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH. 57(10), 3602-3609
• HACKL, CARMEN M., SCHOENHACKER-ALTE, BEATRIX, KLOSE, MATTHIAS H. M., HENKE, HELENA, LEGINA, MARIA S., JAKUPEC, MICHAEL A., BERGER, WALTER, KEPPLER, BERNHARD K., BRUEGGEMANN, OLIVER, TEASDALE, IAN, HEFFETER, PETRA and KANDIOLLER, WOLFGANG, 2017. Synthesis and in vivo anticancer evaluation of poly(organo) phosphazene-based metallodrug conjugates DALTON TRANSACTIONS. 46(36), 12114-12124
• HANIF, MUHAMMAD, MEIER, SAMUEL M., ADHIREKSAN, ZENITA, HENKE, HELENA, MARTIC, SANELA, MOVASSAGHI, SANAM, LABIB, MAHMOUD, KANDIOLLER, WOLFGANG, JAMIESON, STEPHEN M. F., HEJL, MICHAELA, JAKUPEC, MICHAEL A., KRAATZ, HEINZ-BERNHARD, DAVEY, CURT A., KEPPLER, BERNHARD K. and HARTINGER, CHRISTIAN G., 2017. Functionalization of Ruthenium(II)(eta(6)-p-cymene)(3-hydroxy-2-pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies CHEMPLUSCHEM. 82(6), 841-847
• HENKE, HELENA, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2017. Branched Macromolecular Architectures for Degradable, Multifunctional Phosphorus-Based Polymers MACROMOLECULAR RAPID COMMUNICATIONS. 38(4),
• HENKE, HELENA, KRYEZIU, KUSHTRIM, BANFIC, JELENA, THEINER, SARAH, KOERNER, WILFRIED, BRUEGGEMANN, OLIVER, BERGER, WALTER, KEPPLER, BERNHARD K., HEFFETER, PETRA and TEASDALE, IAN, 2016. Macromolecular Pt(IV) Prodrugs from Poly(organo)phosphazenes MACROMOLECULAR BIOSCIENCE. 16(8), 1239-1249
• HENKE, HELENA, POSCH, SANDRA, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2016. Polyphosphazene Based Star-Branched and Dendritic Molecular Brushes MACROMOLECULAR RAPID COMMUNICATIONS. 37(9), 769-774
• WILFERT, SANDRA, ITURMENDI, AITZIBER, HENKE, HELENA, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2014. Thermoresponsive Polyphosphazene-Based Molecular Brushes by Living Cationic Polymerization MACROMOLECULAR SYMPOSIA. 337(1), 116-123
• WILFERT, SANDRA, HENKE, HELENA, SCHOEFBERGER, WOLFGANG, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2014. Chain-End-Functionalized Polyphosphazenes via a One-Pot Phosphine-Mediated Living Polymerization MACROMOLECULAR RAPID COMMUNICATIONS. 35(12), 1135-1141
• HENKE, HELENA, WILFERT, SANDRA, ITURMENDI, AITZIBER, BRUEGGEMANN, OLIVER and TEASDALE, IAN, 2013. Branched Polyphosphazenes with Controlled Dimensions JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY. 51(20), 4467-4473
• HENKE, HELENA, KANDIOLLER, WOLFGANG, HANIF, MUHAMMAD, KEPPLER, BERNHARD K. and HARTINGER, CHRISTIAN G., 2012. Organometallic Ruthenium and Osmium Compounds of Pyridin-2-and-4-ones as Potential Anticancer Agents CHEMISTRY & BIODIVERSITY. 9(9), 1718-1727
• KANDIOLLER, WOLFGANG, KURZWERNHART, ANDREA, HANIF, MUHAMMAD, MEIER, SAMUEL M., HENKE, HELENA, KEPPLER, BERNHARD K. and HARTINGER, CHRISTIAN G., 2011. Pyrone derivatives and metals: From natural products to metal-based drugs JOURNAL OF ORGANOMETALLIC CHEMISTRY. 696(5), 999-1010
• HANIF, MUHAMMAD, HENKE, HELENA, MEIER, SAMUEL M., MARTIC, SANELA, LABIB, MAHMOUD, KANDIOLLER, WOLFGANG, JAKUPEC, MICHAEL A., ARION, VLADIMIR B., KRAATZ, HEINZ-BERNHARD, KEPPLER, BERNHARD K. and HARTINGER, CHRISTIAN G., 2010. Is the Reactivity of M(II)-Arene Complexes of 3-Hydroxy-2(1H)-pyridones to Biomolecules the Anticancer Activity Determining Parameter? INORGANIC CHEMISTRY. 49(17), 7953-7963